Obtaining superparamagnetic nanoparticles (SPMNPs) of (Fe-Co)f (Fe3O4 and CoxFe(3-x)O4, x = 0.1 – 1) and 3D/2D computational study on superparamagnetic hyperthermia (SPMHT) in these nanosystems and bioconjugates with gamma-cyclodextrins ((Fe-Co)f-g-CD))
Stage no. I (year 2020)
Stage no. II (year 2021)
Obtaining and testing SPMNPs (Fe-Co)f-g-CD bionanoconjugates for cell viability/ toxicity and superparamagnetic hyperthermia (SPMHT), and in vitro testing/ validation of the SPMHT method with (Fe-Co)f-g-CD nanobioconjugates on skin and breast cancer
Stage no. III (year 2022)
In vivo (on animal model) testing/ validation of SPMHT using (Fe-Co)f-g-CD nanobioconjugates on skin cancer and breast carcinoma; cytotoxicity/ viability and evaluation of the hyperthermic effect on tumors