Publicaţii

WOS Publications:

– ISI Articles

[1] Costica Caizer, Isabela Simona Caizer, Roxana Racoviceanu, Claudia Geanina Watz, Mioc Marius, Cristina Adriana Dehelean, Tiberiu Bratu, Codruta Marinela Soica, Fe3O4-PAA–(HP-γ-CDs) Biocompatible Ferrimagnetic Nanoparticles for Increasing Efficacy in Superparamagnetic Hyperthermia, NANOMATERIALS, 12 (2022) 2577 (IF: 5.719; Q1 – red area).
 
[2] Isabela Simona Caizer, Costica Caizer, Superparamagnetic Hyperthermia Study with Cobalt Ferrite Nanoparticles Covered with γ-Cyclodextrins by Computer Simulation for Application in Alternative Cancer Therapy, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 23 (2022) 4350 (IF: 6.208; Q1 – red area).
 
[3] Costica Caizer, Computational study regarding CoxFe3-xO4 ferrite nanoparticles with tunable magnetic properties in superparamagnetic hyperthermia for effective alternative cancer therapy, NANOMATERIALS, 11 (2021) 3294 (IF: 5.076; Q1 – red area).
 
[4] Costica Caizer, Isabela Simona Caizer, Study on maximum specific loss power in Fe3O4 nanoparticles decorated with biocompatible gamma-cyclodextrins for cancer therapy with superparamagnetic hyperthermia, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 22 (2021) 10071 (IF: 5.924; Q1 – red area).
 
[5] Elena-Alina Moaca, Claudia Geanina Watz, Vlad Socoliuc, Roxana Racoviceanu, Cornelia Pacurariu, Robert Ianos, Simona Cînta-Pînzaru, Lucian Barbu Tudoran, Fran Nekvapil, Stela Iurciuc, Codruta Şoica, Cristina Adriana Dehelean, Biocompatible magnetic colloidal suspension used as a tool for localized hyperthermia in human breast adenocarcinoma cells: physicochemical analysis and complex in vitro biological profile, NANOMATERIALS, 11 (2021) 1189 (IF: 5.076; Q1 – red area).
 
[6] Costica Caizer, Theoretical study on specific loss power and heating temperature in cofe2o4 nanoparticles as possible candidate for alternative cancer therapy by superparamagnetic hyperthemia, APPLIED SCIENCES, 11 (2021) 5505 (IF: 2.679; Q2 – yellow area).
 
[7] Costica Caizer, Optimization study on specific loss power in superparamagnetic hyperthermia with magnetite nanoparticles for high efficiency in alternative cancer therapy, NANOMATERIALS, 11 (2020) 40 (IF: 5.076; Q1 – red area).
 
– BDI Article:
 
[8] I.S. Caizer, C. Caizer, Cobalt Doped Fe3O4 Nanoparticles for Magnetic Hyperthermia Application, AMERICAN INSTITUTE OF PHYSICS CONFERENCE PROCEEDINGS SERIES, 2022 (BDI, Web of Science), accepted.
 
– WoS Research Books/Chapters:
 
[1] Costica Caizer, Applications in Nanotechnology and Nanomedicine of Magnetic Nanomaterials (Research Special Issue, electronic); In: APPLIED SCIENCES, 2022 (WoS) (under publication).
 
[2] Costica Caizer, Magnetic/Superparamagnetic hyperthermia in clinical trials for noninvasive alternative cancer therapy; In: Magnetic Nanoparticles in Human Health and Medicine: Current Medical Applications and Alternative Therapy of Cancer (Caizer C. and Rai M. (Eds.)), WILEY, 2021, pp. 430463 (WoS)).
 
[3] Costica Caizer, Cristina Dehelean, Codruta Soica, Classical magnetoliposomes vs. current magnetocyclodextrins with ferrimagnetic nanoparticles for high efficiency and low toxicity in noninvasive alternative therapy of cancer by magnetic/superparamagnetic hyperthermia; In: Magnetic Nanoparticles in Human Health and Medicine: Current Medical Applications and Alternative Therapy of Cancer (Caizer C. and Rai M. (Eds.)), WILEY, 2021, pp. 272306 (WoS).
 
[4] Costica Caizer, Cristina Dehelean, Dorina Elena Coricovac, Isabela Simona Caizer, Codruţa Şoica, Magnetic nanoparticle nanoformulations for alternative therapy of cancer by magnetic/superparamagnetic hyperthermia; In: Nanoformulations in Human Health (Talegaonkar S. and Rai M. (eds.)), SPRINGER, 2020, pp. 503530 (WoS).
 

Conferințe

1. Costica Caizer, Isabela Simona Caizer, Roxana Racoviceanu, Claudia Geanina Watz, Mioc Marius, Cristina Adriana Dehelean, Tiberiu Bratu, Codruta Marinela Soica, 3NANO-22 Nano Science/Technology/Biotechnology International Conference, 20-23 Sept., Roma, 2022 (accepted).

 

2. C. Caizer, I.S. Caizer, C. Soica, R. Racoviceanu, M. Mihoc, The (Co-Fe)f ferrite biocompatible magnetic nanoparticles for increasing efficacy and reducing toxicity in superparamagnetic hyperthermia for alternative cancer therapy, 13th International Conference on Physics of Advanced Materials (ICPAM-13), September 2430, 2021, Sant Feliu de Guixols, Spain. Abstract Book: pp. 4749

 

3. R. Racoviceanu, M. Mioc, C. Soica, C. Caizer and I.S. Caizer, Cobalt doped Fe3O4 nanoparticles – synthesis, characterization and magnetic hyperthermia application, TIM 20-21 Physics Conference, November 11th13th, 2021, Timisoara, Romania. Abstract Book: API-O12.

 

National Conference:
4. Roxana Racoviceanu, Marius Mioc, Roxana Ghiulai, Alexandra Ulici, Andreea Milan, Codruța Șoica, Synthesis and characterization of cobalt doped magnetite nanoparticles destined for hyperthermia applications, Congresul National de Farmacie, Ed. XVIII, 1517 sept., 2021, Oradea, Romania. ID: 254.

New Nanobiomaterial

Nanobioproduct (EM: experimental model): superparamagnetic (SPM) bionanoconjugates of (Fe-Co)f-PAA-(HP-g-CDs) for use in breast (MCF-7) and skin (melanoma A375 and squamous A431) cancer therapy with increased effectiveness and reduced toxicity through superparamagnetic hyperthermia (SPMHT);
(1) SPM Fe3O4-PAA-(HP-g-CDs) bionanoconjugates;
(2) SPM Co0.05Fe2.95O4-PAA-(HP-g-CDs) bionanoconjugates;
(3) SPM Co0.1Fe2.9O4-PAA-(HP-g-CDs) bionanoconjugates;
(4) SPM Co0.2Fe2.8O4-PAA-(HP-g-CDs) bionanoconjugates;
(5) SPM CoFe2O4-PAA-(HP-g-CDs) bionanoconjugates;
PAA – polyacrylic acid; (HP-g-CDs) – hydroxypropyl gamma-cyclodextrins;

Protocol

Application of superparamagnetic hyperthermia (SPMHT) with SPM nanobioconjugates of (Fe-Co)f-PAA-(HP-g-CDs) ((Fe-Co)f is Fe3O4 (P1 magnetic sample), Co0.05Fe2.95O4 (P2 magnetic sample) and CoFe2O4 (P6 magnetic sample), PAA is polyacrylic acid, (HP-g-CDs) is hydroxypropyl gamma-Cyclodextrin) in vitro on tumor cell cultures and in vivo on the animal model with induced cancer, for the alternative therapy of skin cancer (melanoma (A375), squamous (A431)) and breast cancer (MCF-7).

Cele mai semnificative rezultate obținute în proiect